上海同济大学 生命科学与技术学院 张晓艳（副教授）导师简介

个人简介

2006 －现在：同济大学生命科学与技术学院

2000－2003：复旦大学生命科学学院植物学专业博士生，2003年6月获理学博士学位

1998－1999：美国密执安州立大学林学系博士生

1995－1997：美国新墨西哥州高地大学生命科学学院硕士生，1997年12月获科学硕士学位

1984－2000：中国科学院武汉植物研究所

 

主要科研项目：

2012－2014：人乳头瘤病毒HPV与内源性miRNA相互作用模型的建立及其致癌危险性研究，自然科学基金（合作申请）

2008－2011：利用小鼠基因剔除技术发现新的基因工程药物，863计划 副组长

2007－2010：建立基于临床医疗信息共享平台的医疗决策支持系统，863计划 主要参加者

2003－2007：基因功能预测的系统发育分析模型与检验方法, 973项目 主要参加者

 

近年发表文章情况：

1． Xin Zhao, Qi Liu, Qingqing Cai, Yanyun Li, Congjian Xu, Yixue Li, Zuofeng Li,*and Xiaoyan Zhang1,* Dr.VIS: a database of human disease-related viral integration sites, Nucl. Acids Res. (2011) Nucleic Acids Research, 2012, Vol. 40, Database issue D1041–D1046（SCI 通讯作者）

2． Zuofeng Li, Xingnan Liu, Jingran Wen,Y, e Xu, Xin Zhao, Xuan Li, Lei Liu*, and Xiaoyan Zhang,* DRUMS: A human disease related unique gene mutation search engine, 2011, HUMAN MUTATION Database in Brief 32: E2259-E2265 (2011) Online （SCI 通讯作者）

3． Yang Yang, Zuofeng Li, Peng Nan, Xiaoyan Zhang*,2011，Drug-induced glucose-6-phosphate dehydrogenase deficiency-related hemolysis risk assessment, Computational Biology and Chemistry 35 (2011) 189–192 (SCI 通讯作者)

4． Wei W.Q., Liu F.Q., Liu L., Li Z.F., Zhang X.Y., Jiang F., Shi Q., Zhou X.Y., Sheng W.Q., Cai S.J., Li X., Xu Y., Nan P. Distinct mutations in MLH1 and MSH2 genes in Hereditary Non-polyposis Colorectal Cancer (HNPCC) families from China. BMB Rep, 2011 May;44(5):317-22. (SCI )

5． Liu Xinyi, Li Zuofeng,Cai Qingqing，Zhang Xiaoyan*. Prediction of multiple drug resistance phenotype in cancer cell lines using gene expression profiles and phylogenetic trees. Chinese Sci Bull, 2010, 55: 3778−3786 （SCI 通讯作者）

6． Xin Zhao, Zoufeng Li, Xiaoyan Zhang*. 2010. G6PD-MutDB: A MUTATION AND PHENOTYPE DATABASE OF GLUCOSE-6-PHOSPHATE (G6PD) DEFICIENCY. Journal of Bioinformatics and Computational Biology. Volume: 8, Supplementary Issue 1(2010) pp. 101-1099

7． Qingqing Cai, Zoufeng Li, Xiaoyan Zhang*. MiRNAs as promising phylogenetic markers for inferring deep metazoan phylogeny and in support of Olfactores hypothesis. BIBM'2010. pp.101~104

8． Qiang Zeng, Xiaoyan Zhang*…., Extracting Clinical Information from Free-text of Pathology and Operation Notes via Chinese Natural Language Processing, 2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops

9． Liu Xinnan, Xu Ye, Li Zuofeng, Liu Lei and Zhang Xiaoyan*，2009，ESCPP: An Evaluation and Alerting System for the Compatibility between Practice Guidelines and Practicing Medicine Using Arden Syntax

10． Wen Jingran, Zhang XIaoyan*, Xu Ye, Li Zuofeng and Liulei, Comparation of AdaBoost and Logistic Regression for Detection Colorectal Cancer Patients with Synchronous Liver Metastasis（ICBPE2009）(EI Accession number:20101612851195)

11． Gong Cheng,1,* Xin Zhao,1,* Zuofeng Li, Xinyi Liu, Weiyao Yan, Xiaoyan Zhang, Yang Zhong, and Zhaoxin Zheng1Identification of a Putative Invertebrate Helical Cytokine Similar to the Ciliary Neurotrophic Factor/Leukemia Inhibitory Factor Family by PSI-BLAST-Based Approach,2009 Journal of Interferon & Cytokine Research,Vol 29(8) 462-468 (SCI ）

12． HAO Pei，YU Yao, ZHANG Xiaoyan, …etc. The contribution of cis-regulatory elements to head-to-head gene pairs’ co-expression pattern, Sci China Ser C-Life Sci Jan.2009,52(1)74-79 (SCI ）