近年来共发表10余篇论文,包括SCI收入国际核心期刊论文10篇。
科研基金及其完成情况:
在研项目
1. 2007-2011 项目分课题参加
项目名称: 血吸虫感染的免疫应答及调控机制(课题号2007CB513106)
国家973重点基础研究发展计划:疟疾、血吸虫病防治的基础研究
(项目号2007CB513100)
资助来源: 科技部重大科学研究计划
经费: 70万元人民币
2.01-2011-12-2014 课题负责人
项目名称: 嗜碱性粒细胞在日本血吸虫感染Th2免疫应答及免疫病理中的作用(课题号81071382)
资助来源: 国家自然科学基金
经费: 35万
论文发表:
1.He Y , Li J , Zhuang WJ, Yin L, Chen C , Li J , Chi F, Bai Y, Chen X-P . The inhibitory effect against collagen-induced arthritis by Schistosoma japonicum infection is infection stage-dependent. BMC Immunology 11:28,2010
2. 丛莉,陈小平。嗜碱性粒细胞在介导Th2免疫应答中的作用。现代免疫学 2011
3. 和云鹍,陈小平。蠕虫感染与过敏性疾病和自身免疫病。国际免疫学杂志 32(3):219-222,2009
4.殷燕,陈小平。 血吸虫虫卵多聚糖的免疫调节作用 国际医学寄生虫病杂志 35(6):316-319,2008
5.Chen Y-Z and Chen X-P Do we need molecular tomography of a cell? Clinical and Experimental Pharmacology and Physiology 35:872–877, 2008
6.李佳,陈小平。Th效应细胞家族的新成员——Th17。 中国免疫学杂志 23(11):1048-1051,2007
7. Chen X-P , D. Falkner and P. Morel. Impaired IL-4 production by CD8+ T cells in NOD mice is related to a defect of c-Maf binding to the IL-4 promoter. Eur J Immunol 35(5):1408-17, 2005
8. Chen X-P, Mata M, Kelley M, Wolfe D, Glorioso JC and Fink DJ. The relationship of LAT expression to genome copy number: Quantative single cell analysis of herpes simplex virus type 1 latency using laser capture microdissection. J Neurovirology 8:204-210, 2002
9. Chen X-P, Li J, Goss J, Wolfe D, Glorioso JC and Fink DJ. The ICP0 protein of herpes simplex virus 1 does not accumulate in the nucleus of primary neurons in culture. J Virology 74(21):10132-10141, 2000.
10. Liu T, Khanna KM, Chen X-P, Fink DJ and Hendricks RL. CD8+ T Cell can block Herpes simplex virus I (HSV-1) reactivation from latency in sensory neurons. J Exp Med 191(9): 1459-1466, 2000
11.Chen, X-P., X. Ding, and R.A. Daynes. Ganglioside Control Over IL-4 Priming
and Type 2 Cytokine Production in Activated T Cells. Cytokines 12(7):972-985, 2000
12. Chen X-P, Enioutina EY and Daynes RA . The control of IL-4 gene expression
in activated murine T lymphocytes: a novel role for neu-1 sialidase. J Immunol. 158(7): 3070-80, 1997
11.Poynter ME, Mu HH, Chen X-P, Daynes RA. Activation of NK1.1+ T cells in vitro and their possible role in age-associated changes in inducible IL-4 production. Cell Immunol 179(1):22-9, 1997
12.Hennebold JD, Mu HH, Poynter ME, Chen X-P, Daynes RA. Active Catabolism
of glucocorticoids by 11 beta-hydroxysteroid dehydrogenase in vivo is a necessary requirement for natural resistance to infection with Listeria monocytogenes. Int Immunol 9(1):105-15, 1997
书:
X-P Chen and DJ Fink. Use of laser capture microdissection together with in situ hybridization and real-time PCR to study the distribution of latent herpes simplex virus genomes in mouse trigeminal ganglion. In Murray, G. I. And Curran. S (Eds.) Laser Capture Microdissection. Methods and Protocols. Humana Press, Totowa, NJ 2004, pp285-293.